What is Semaglutide?
Semaglutide is a long-acting GLP-1 receptor agonist with 94% homology to native human GLP-1. Chemical modifications (fatty-acid side-chain, amino-acid substitutions) extend its half-life to ~1 week, enabling once-weekly dosing.
The STEP clinical program established the category benchmark for pharmacological weight management: ~15% mean body-weight reduction over 68 weeks in a non-diabetic cohort.


